Lipids in Agronomy, Health and Disease : Congres GERLI, 25 octobre - 28 novembre, Strasbourg, France
Colin, J., Huguet, M., Derrien, A., Yen Potin, F., Malaplate-Armand, C., Oster, T.
2015
In the demographic context of the continuously increasing lifespan in Western countries, the rise of chronic diseases related to aging, including Alzheimer’s disease and other dementia types, has become a major public health issue. The chronic impact of many modifiable risk factors and the lack of curative treatments illustrate the need for the development of preventive interventions to minimize the onset of these age-related diseases. The present study focused on the effects of aging and high-fat diet-induced dyslipidemia on the properties of cortical membrane extracted from mouse brain. Our results clearly identified the neuronal membranes as essential biological entities for normal brain function. We showed that aging led to composition and architectural changes in membrane microdomain organization. These changes were associated with the exclusion of CNTF (ciliary neurotrophic factor) receptor subunits from the lipid rafts, resulting in disruption of the associated STAT3 and ERK1/2 signalization pathways. We also observed similar pro-aging type changes in brain membranes of dyslipidemic mice fed a high-fat diet. Such a functional disruption also reduced the neuroprotective responsiveness to CNTF, such as those sought by anti-Alzheimer’s therapies. These data suggested that disturbances of lipid homeostasis could be correlated with increased risk of developing age-related cardiovascular and metabolic as well as neurodegenerative diseases. We finally demonstrated the potential of dietary supplementation with docosahexaenoic acid (C22:6, ?3), the most abundant long-chain polyunsaturated fatty acid in the brain, in preventing CNTF receptor delocalization and disruption, and observed its ability to preserve a neuroprotective response that was impaired in older mice. The results of our study demonstrate the importance of taking into account the aging factor when designing appropriate animal models for a better understanding of the deleterious processes of age-related diseases. Our observations also validate the functional interest of combining pharmacological treatments and preventive nutritional approaches based on polyunsaturated fatty acids ?3 to preserve the neuronal membrane responsiveness in the elderly, in order to minimize brain aging and to optimize the efficiency of anti-Alzheimer’s therapeutic molecules and approaches.
European Aquaculture Society EAS, 18-21 septembre, Vienne, Autriche
Al Dakdouki, S., Fontaine, P., Ledore, Y., Nivelle, R., Changey, F.
7ème conference Panafrican Association on Fish and Fisheries, 18-22 septembre, Brazzaville, République du Congo
Amoussou, N., Lecocq, T., Pasquet, A., Thomas, M.
Aquaculture Europe 2023, 19-21 septembre, Vienne, Autriche
Bernath, G., Milla, S., Várkonyi, L., Ledore, Y., Griffitts, J.D., Fontaine, P., Urbányi, B., Bokor, Z.
74th Annual Meeting of European Federation of Animal Science, 28-31 août, Lyon, France
Collas, C., Laflotte, A., Feidt, C., Jurjanz, S.
Aquaculture Europe 2023, Balanced Diversity in Aquaculture Development, 18-21 septembre, Vienne, Autriche
Diakos, E., Fontaine, P., Lecocq, T.
Aquaculture Europe 2023, Balanced Diversity in Aquaculture Development, 18-21 septembre, Vienne, Autriche
Diakos, E., Pasquet, A., Hardy, A., Chevalier, C., Fontaine, P., Lecocq, T.
Aquaculture Europe 2023, Balanced Diversity in Aquaculture Development, 18-21 septembre, Vienne, Autriche
Fontaine, P., Lecocq, T., Thomas, M.
74th European Federation of Animal Science Congress, 26 août - 01 septembre, Lyon, France
Fournier, A., Feidt, C., Fourcot, A., Saint-Hilaire, M., Le Roux, Y., Rychen, G.
Symposium for European Freshwater Sciences, 18-21 septembre, New Castle Upon Tyne, United Kingdom
Girard, L., Aubin, J., Thomas, M., Lecocq, T., Robin, J., Tocqueville, A., Laithier, J., Pannard, A., Coudreuse, J., Roucaute, M., Jaeger, C., Wilfart, A., Latourre, Q., Maillot, M., Corson, M.
12th International Symposium on Reproductive Physiology of Fish, 15-19 mai, Crete, Greece
Schaerlinger, B., Fontagne-dicharry, S., Gasmi, S., Durante-alami, H., Ledore, Y., Fontaine, P., Nahon, S., Chardard, D.
Aquaculture Europe 2023, Balanced Diversity in Aquaculture Development, 18-21 septembre, Vienne, Autriche
Thomas, M., Amoussou, N., Pasquet, A., Lecocq, T.
Aquaculture Europe, 27-30 septembre, Rimini, Italie
Aubin, J., Thomas, M., Lecocq, T., Robin, J., Dupont, C., Tocqueville, A., Laithier, J., Pannard, A., Coudreuse, J., Roucaute, M., Jaeger, C., Wilfart, A., Maillot, M., Corson, M.S.
73rd Annual Meeting of European Federation of Animal Science, 05-08 septembre, Porto, Portugal
Collas, C., Briot, L., Fleurance, G., Dozias, D., Launay, F., Feidt, C., Jurjanz, S.
73rd Annual Meeting of European Federation of Animal Science, 05-08 septembre, Porto, Portugal
Collas, C., Gourdine, J.-L., Beramine, D., Badot, P.-M., Feidt, C., Jurjanz, S.
8th international workshop on the biology of fish gametes. Gametes workshop., 20-23 septembre, Gdansk, Pologne
Ljubobratovic, U., Kitanovic, N., Milla, S., Marinovic, Z., Fazekas, G., Stanivuk, J., Zarski, D., Horvath, A.
5th International Percid Fish Symposium - Percis V, 18-23 septembre, Ceske Budejovice, Czech Republic
Senff, P., Fourrier, C., Abd Al Rahim, S., Gerard, E., Milla, S., Nivelle, R., Fontaine, P.
Aquaculture Europe 2022, 27-30 septembre, Rimini, Italy
Senff, P., Gerard, E., Polowczyk, O., Piga, V., Grosjean, J., Robin, C., Fontaine, P.
Aquaculture Europe 2021, 05-08 octobre, Madère, Portugal
Amoussou, N., Lecocq, T., Pasquet, A., Thomas, M.
FishBase SeaLifeBase Symposium, 30 years of FishBase – 15 years of FishBase, 06 septembre - 07 septembre, Paris, France
Chardard, D., Willig, C., Bailly, N., Atanacio, R., Fordoxcel, L., Delaunay, S., Gerard, P.-A., Teletchea, F.
1st Franco-Canadian of Aquatic Sciences, Saint-Pierre and Miquelon, 30 septembre - 03 octobre, Saint-Pierre et Miquelon, France
Detcheverry, E., Lemallier, E., Teletchea, F.
1st Franco-Canadian of Aquatic Sciences, Saint-Pierre and Miquelon, 30 septembre - 03 octobre, Saint-Pierre et Miquelon, France
Durand, E., Gustave, E., Vasconcelos, R., Perrin, L., Drogue, G., Teletchea, F.
Colloque Aquaculture Europe 2021, 04-07 octobre, Madeira, Portugal
El Mohajer, L., Chevalier, C., Fontaine, P., Milla, S.
Franco-Canadian Congress of Aquatic Sciences, 30 septembre - 03 octobre, Saint-Pierre-et-Miquelon, France
Fontaine, P.
2ème Conférence Internationale POLYSAC 2021, 11-13 décembre, SFAX, TUNISIE
Hentati, F., Narmuratova, Z., Girardet, J.-M., Narmuratova, M., Cakir-Kiefer, C.
Aquaculture Europe 2021, 05-08 octobre, Madère, Portugal
Lecocq, T., Toomey, L., Fontaine, P.
1st Franco-Canadian of Aquatic Sciences, Saint-Pierre and Miquelon, 30 septembre - 03 octobre, Saint-Pierre et Miquelon, France
Lecointre, G., Schnell, N., Teletchea, F.
Aquaculture Europe 2021, 05-08 octobre, Madère, Portugal
Senff, P., Polowczyk, O., Grosjean, J., Milla, S., Robin, C., Fontaine, P.
1st Franco-Canadian of Aquatic Sciences, Saint-Pierre and Miquelon, 30 septembre - 03 octobre, Saint-Pierre et Miquelon, France
Teletchea, F.
1st Franco-Canadian of Aquatic Sciences, Saint-Pierre and Miquelon, 30 septembre - 03 octobre, Saint-Pierre et Miquelon, France
Teletchea, F.
FishBase SeaLifeBase Symposium, 30 years of FishBase – 15 years of FishBase, 06-07 septembre, Paris, France
Teletchea, F., Union des conservateurs d'aquariums, Barthelemy, D.
1st Franco-Canadian of Aquatic Sciences, Saint-Pierre and Miquelon, 30 septembre - 03 octobre, Saint-Pierre et Miquelon, France
Teletchea, S., Venturelli, P., Teletchea, F.
1st Franco-Canadian of Aquatic Sciences, Saint-Pierre and Miquelon, 30 septembre - 03 octobre, Saint-Pierre et Miquelon, France
Viana, J., Briand, E., Gustave, E., Perrin, L., Vasconcelos, R., Audet, C., Teletchea, F.
Neurodegenerative Diseases: Biology & Therapeutics 2020, 02-04 décembre, Virtual meeting, USA
Vigier, M., Herzine, A., Djelti, F., Yen, F., Oster, T., Malaplate, C.
3th international conference on fish and shellfish immunology, 16-20 juin, Las Palmas, Spain
Baekelandt, S., Milla, S., Cornet, V., Flamion, E., Ledore, Y., Redivo, B., Antipine, S., Mandiki, S.N.M., El Kertaoui, N., Schmitz, M., Kestemont, P.
Biomolecules: Research & Development, Markets and Acceptability, 23-25 octobre, Palma de Majorque, Espagne
Barrau, S., Gaiani, C., Retourney, C., Mangavel, C., Le Roux, Y., Soligot-Hognon, C., Delannoy, M., Scher, J., Burgain, J.
3rd Summer Shoal 2019 on Fish Ethology & Welfare, 10 septembre - 13 novembre, Algarve, Portugal
Colchen, T., Teletchea, F., Ysnel, F., Carpentier, A., Trancart, T., Feunteun, E., Fontaine, P., Pasquet, A.
DIXOIN 2019 - 39th International Symposium on Halogenated Persistent Organic Pollutant, 25 août - 30 août, Kyoto, Japon
Coulange, M., Fourcot, A., Fournier, A., Narduzzi, L., Rychen, G., Le Bizec, B., Feidt, C., Dervilly, G.
EAS Aquaculture Europe, 07-10 octobre, Berlin, Allemagne
El Mohajer, L., Selmi, S., Fontaine, P., Milla, S.
70th Annual Meeting of the European Federation of Animal Science, 26-30 août, Ghent, Belgium
Germain, K., Collas, C., Brachet, M., Jurjanz, S.
70th Annual Meeting of the European Federation of Animal Science, 26-30 août, Ghent, Belgium
Jurjanz, S., Collas, C., Quish, C., Younge, B., Feidt, C.
70th Annual Meeting of the European Federation of Animal Science, 26-30 août, Ghent, Belgium
Quish, C., Arkins, S., Jurjanz, S., Collas, C., Feidt, C., Younge, B.
43rd larval fish conference, 21-24 juin, Mallorca, Espagne
Teletchea, F., Schnell, N., Lecointre, G.
European Aquaculture, 07-11 octobre, Berlin, Allemagne
Thomas, M., Pasquet, A., Ledore, Y., Schaeffer, L., Nahon, S., Aubin, J., Jaeger, C., Wilfart, A., Benard, A., Lecocq, T.
XVI European Congress of Ichthyology, Lausanne, Switzerland, 2 Sep - 6 Sep
Toomey, L., Fontaine, P., Lecocq, T.
9th Biennial Conference of the International Biogeography Society, 08-12 janvier, Malaga, Espagne
Toomey, L., Pasquet, A., Teletchea, F., Fontaine, P., Lecocq, T.
43rd larval fish conference, 21-24 juin, Mallorca, Espagne
Venturelli, P., Teletchea, F.
70th EAAP Annual Meeting, 26-30 august, Ghent, Belgium
Viel, J., Ringuet, A., Mauclert, J., Laclef, E., Jurjanz, S.
Aquaculture Europe 2019, 07-10 octobre, Berlin, Allemagne
Zarski, D., Bernath, G., Ben Ammar, I., Mandiki, S.N.M., Baekelandt, S., Bokor, Z., Fontaine, P., Horvath, A., Kestemont, P.
Aquaculture Europe 2019, 07-10 octobre, Berlin, Allemagne
Zarski, D., Le Cam, A., Nynca, J., Klopp, C., Montfort, J., Fontaine, P., Ciereszko, A., Bobe, J.
7th International workshop of the biology of fish gametes, 02-06 septembre, Rennes, France
Zarski, D., Nynca, J., Le Cam, A., Klopp, C., Montfort, J., Fontaine, P., Ciereszko, A., Bobe, J.