Arteriosclerosis, Thrombosis and Vascular Biology / Peripheral Vascular Disease Meeting, 07-09 mai, San Francisco, Etats-Unis
Yassine, H.-N., Ramrakhiani, A., Parekh, A., Walker, R., Goran, M., Trenchevska, O., Nedelkov, D., Nelson, R., Koska, J., Reaven, P.-D., Hayden, C.-T., Yen, F.T.
2015
Apo CIII inhibits lipoprotein lipase activity and remnant particle uptake in the liver by the lipolysis stimulated receptor (LSR); and therefore modulates liver and systemic lipid metabolism. Although post-translational modifications of apolipoprotein (apo) CIII lead to asialylated, mono- or disialylated variants, the biological relevance of these sialylations is not known. Our objective was to determine whether sialylated variants of apo CIII regulate lipoprotein triglyceride metabolism and development of fatty liver. In 223 obese non-diabetic adolescent Hispanic participants, apo CIII variants in plasma were measured using mass spectrometric immunoassay. Analysis of apo CIII revealed that the increased plasma ratio of di- to mono-sialylated CIII was associated with lower triglyceride levels (r=-0.43, p<0.001), and less liver fat by MRI (r=-0.27, p<0.001) independent of total apo CIII concentrations. Higher plasma concentrations of the mono-sialylated, but not the di-sialylated variant, were associated with higher triglycerides concentrations (r=0.53, p<0.001). Using HepG2 liver cells, we demonstrated that immunoprecipitated apo CIII from VLDL of participants in the upper quartile of di-sialylated to mono-sialylated CIII ratio less effectively inhibited LSR-mediated VLDL uptake compared with CIII isolated from VLDL of participants in the lower quartile of CIII sialylation ratio. This effect on VLDL uptake was abolished by removal of sialic acid with neuraminidase. VLDL particles with higher apo CIII sialylation were also enriched with ApoE. Apo CIII isolated from VLDL of participants in the upper or lower quartile of CIII sialation ratio demonstrated a similar capacity to inhibit fatty acid release by lipoprotein lipase ex vivo. We conclude that a greater ratio of di-sialylated to mono-sialylated apo CIII together with particle enrichment in apo E allow for more efficient VLDL liver uptake and is associated with less liver fat. The measurement of apo CIII sialylation in plasma may be a useful index of triglyceride metabolism and risk of fatty liver.
European Aquaculture Society EAS, 18-21 septembre, Vienne, Autriche
Al Dakdouki, S., Fontaine, P., Ledore, Y., Nivelle, R., Changey, F.
7ème conference Panafrican Association on Fish and Fisheries, 18-22 septembre, Brazzaville, République du Congo
Amoussou, N., Lecocq, T., Pasquet, A., Thomas, M.
Aquaculture Europe 2023, 19-21 septembre, Vienne, Autriche
Bernath, G., Milla, S., Várkonyi, L., Ledore, Y., Griffitts, J.D., Fontaine, P., Urbányi, B., Bokor, Z.
74th Annual Meeting of European Federation of Animal Science, 28-31 août, Lyon, France
Collas, C., Laflotte, A., Feidt, C., Jurjanz, S.
Aquaculture Europe 2023, Balanced Diversity in Aquaculture Development, 18-21 septembre, Vienne, Autriche
Diakos, E., Fontaine, P., Lecocq, T.
Aquaculture Europe 2023, Balanced Diversity in Aquaculture Development, 18-21 septembre, Vienne, Autriche
Diakos, E., Pasquet, A., Hardy, A., Chevalier, C., Fontaine, P., Lecocq, T.
Aquaculture Europe 2023, Balanced Diversity in Aquaculture Development, 18-21 septembre, Vienne, Autriche
Fontaine, P., Lecocq, T., Thomas, M.
74th European Federation of Animal Science Congress, 26 août - 01 septembre, Lyon, France
Fournier, A., Feidt, C., Fourcot, A., Saint-Hilaire, M., Le Roux, Y., Rychen, G.
Symposium for European Freshwater Sciences, 18-21 septembre, New Castle Upon Tyne, United Kingdom
Girard, L., Aubin, J., Thomas, M., Lecocq, T., Robin, J., Tocqueville, A., Laithier, J., Pannard, A., Coudreuse, J., Roucaute, M., Jaeger, C., Wilfart, A., Latourre, Q., Maillot, M., Corson, M.
12th International Symposium on Reproductive Physiology of Fish, 15-19 mai, Crete, Greece
Schaerlinger, B., Fontagne-dicharry, S., Gasmi, S., Durante-alami, H., Ledore, Y., Fontaine, P., Nahon, S., Chardard, D.
Aquaculture Europe 2023, Balanced Diversity in Aquaculture Development, 18-21 septembre, Vienne, Autriche
Thomas, M., Amoussou, N., Pasquet, A., Lecocq, T.
Aquaculture Europe, 27-30 septembre, Rimini, Italie
Aubin, J., Thomas, M., Lecocq, T., Robin, J., Dupont, C., Tocqueville, A., Laithier, J., Pannard, A., Coudreuse, J., Roucaute, M., Jaeger, C., Wilfart, A., Maillot, M., Corson, M.S.
73rd Annual Meeting of European Federation of Animal Science, 05-08 septembre, Porto, Portugal
Collas, C., Briot, L., Fleurance, G., Dozias, D., Launay, F., Feidt, C., Jurjanz, S.
73rd Annual Meeting of European Federation of Animal Science, 05-08 septembre, Porto, Portugal
Collas, C., Gourdine, J.-L., Beramine, D., Badot, P.-M., Feidt, C., Jurjanz, S.
8th international workshop on the biology of fish gametes. Gametes workshop., 20-23 septembre, Gdansk, Pologne
Ljubobratovic, U., Kitanovic, N., Milla, S., Marinovic, Z., Fazekas, G., Stanivuk, J., Zarski, D., Horvath, A.
5th International Percid Fish Symposium - Percis V, 18-23 septembre, Ceske Budejovice, Czech Republic
Senff, P., Fourrier, C., Abd Al Rahim, S., Gerard, E., Milla, S., Nivelle, R., Fontaine, P.
Aquaculture Europe 2022, 27-30 septembre, Rimini, Italy
Senff, P., Gerard, E., Polowczyk, O., Piga, V., Grosjean, J., Robin, C., Fontaine, P.
Aquaculture Europe 2021, 05-08 octobre, Madère, Portugal
Amoussou, N., Lecocq, T., Pasquet, A., Thomas, M.
FishBase SeaLifeBase Symposium, 30 years of FishBase – 15 years of FishBase, 06 septembre - 07 septembre, Paris, France
Chardard, D., Willig, C., Bailly, N., Atanacio, R., Fordoxcel, L., Delaunay, S., Gerard, P.-A., Teletchea, F.
1st Franco-Canadian of Aquatic Sciences, Saint-Pierre and Miquelon, 30 septembre - 03 octobre, Saint-Pierre et Miquelon, France
Detcheverry, E., Lemallier, E., Teletchea, F.
1st Franco-Canadian of Aquatic Sciences, Saint-Pierre and Miquelon, 30 septembre - 03 octobre, Saint-Pierre et Miquelon, France
Durand, E., Gustave, E., Vasconcelos, R., Perrin, L., Drogue, G., Teletchea, F.
Colloque Aquaculture Europe 2021, 04-07 octobre, Madeira, Portugal
El Mohajer, L., Chevalier, C., Fontaine, P., Milla, S.
Franco-Canadian Congress of Aquatic Sciences, 30 septembre - 03 octobre, Saint-Pierre-et-Miquelon, France
Fontaine, P.
2ème Conférence Internationale POLYSAC 2021, 11-13 décembre, SFAX, TUNISIE
Hentati, F., Narmuratova, Z., Girardet, J.-M., Narmuratova, M., Cakir-Kiefer, C.
Aquaculture Europe 2021, 05-08 octobre, Madère, Portugal
Lecocq, T., Toomey, L., Fontaine, P.
1st Franco-Canadian of Aquatic Sciences, Saint-Pierre and Miquelon, 30 septembre - 03 octobre, Saint-Pierre et Miquelon, France
Lecointre, G., Schnell, N., Teletchea, F.
Aquaculture Europe 2021, 05-08 octobre, Madère, Portugal
Senff, P., Polowczyk, O., Grosjean, J., Milla, S., Robin, C., Fontaine, P.
1st Franco-Canadian of Aquatic Sciences, Saint-Pierre and Miquelon, 30 septembre - 03 octobre, Saint-Pierre et Miquelon, France
Teletchea, F.
1st Franco-Canadian of Aquatic Sciences, Saint-Pierre and Miquelon, 30 septembre - 03 octobre, Saint-Pierre et Miquelon, France
Teletchea, F.
FishBase SeaLifeBase Symposium, 30 years of FishBase – 15 years of FishBase, 06-07 septembre, Paris, France
Teletchea, F., Union des conservateurs d'aquariums, Barthelemy, D.
1st Franco-Canadian of Aquatic Sciences, Saint-Pierre and Miquelon, 30 septembre - 03 octobre, Saint-Pierre et Miquelon, France
Teletchea, S., Venturelli, P., Teletchea, F.
1st Franco-Canadian of Aquatic Sciences, Saint-Pierre and Miquelon, 30 septembre - 03 octobre, Saint-Pierre et Miquelon, France
Viana, J., Briand, E., Gustave, E., Perrin, L., Vasconcelos, R., Audet, C., Teletchea, F.
Neurodegenerative Diseases: Biology & Therapeutics 2020, 02-04 décembre, Virtual meeting, USA
Vigier, M., Herzine, A., Djelti, F., Yen, F., Oster, T., Malaplate, C.
3th international conference on fish and shellfish immunology, 16-20 juin, Las Palmas, Spain
Baekelandt, S., Milla, S., Cornet, V., Flamion, E., Ledore, Y., Redivo, B., Antipine, S., Mandiki, S.N.M., El Kertaoui, N., Schmitz, M., Kestemont, P.
Biomolecules: Research & Development, Markets and Acceptability, 23-25 octobre, Palma de Majorque, Espagne
Barrau, S., Gaiani, C., Retourney, C., Mangavel, C., Le Roux, Y., Soligot-Hognon, C., Delannoy, M., Scher, J., Burgain, J.
3rd Summer Shoal 2019 on Fish Ethology & Welfare, 10 septembre - 13 novembre, Algarve, Portugal
Colchen, T., Teletchea, F., Ysnel, F., Carpentier, A., Trancart, T., Feunteun, E., Fontaine, P., Pasquet, A.
DIXOIN 2019 - 39th International Symposium on Halogenated Persistent Organic Pollutant, 25 août - 30 août, Kyoto, Japon
Coulange, M., Fourcot, A., Fournier, A., Narduzzi, L., Rychen, G., Le Bizec, B., Feidt, C., Dervilly, G.
EAS Aquaculture Europe, 07-10 octobre, Berlin, Allemagne
El Mohajer, L., Selmi, S., Fontaine, P., Milla, S.
70th Annual Meeting of the European Federation of Animal Science, 26-30 août, Ghent, Belgium
Germain, K., Collas, C., Brachet, M., Jurjanz, S.
70th Annual Meeting of the European Federation of Animal Science, 26-30 août, Ghent, Belgium
Jurjanz, S., Collas, C., Quish, C., Younge, B., Feidt, C.
70th Annual Meeting of the European Federation of Animal Science, 26-30 août, Ghent, Belgium
Quish, C., Arkins, S., Jurjanz, S., Collas, C., Feidt, C., Younge, B.
43rd larval fish conference, 21-24 juin, Mallorca, Espagne
Teletchea, F., Schnell, N., Lecointre, G.
European Aquaculture, 07-11 octobre, Berlin, Allemagne
Thomas, M., Pasquet, A., Ledore, Y., Schaeffer, L., Nahon, S., Aubin, J., Jaeger, C., Wilfart, A., Benard, A., Lecocq, T.
XVI European Congress of Ichthyology, Lausanne, Switzerland, 2 Sep - 6 Sep
Toomey, L., Fontaine, P., Lecocq, T.
9th Biennial Conference of the International Biogeography Society, 08-12 janvier, Malaga, Espagne
Toomey, L., Pasquet, A., Teletchea, F., Fontaine, P., Lecocq, T.
43rd larval fish conference, 21-24 juin, Mallorca, Espagne
Venturelli, P., Teletchea, F.
70th EAAP Annual Meeting, 26-30 august, Ghent, Belgium
Viel, J., Ringuet, A., Mauclert, J., Laclef, E., Jurjanz, S.
Aquaculture Europe 2019, 07-10 octobre, Berlin, Allemagne
Zarski, D., Bernath, G., Ben Ammar, I., Mandiki, S.N.M., Baekelandt, S., Bokor, Z., Fontaine, P., Horvath, A., Kestemont, P.
Aquaculture Europe 2019, 07-10 octobre, Berlin, Allemagne
Zarski, D., Le Cam, A., Nynca, J., Klopp, C., Montfort, J., Fontaine, P., Ciereszko, A., Bobe, J.
7th International workshop of the biology of fish gametes, 02-06 septembre, Rennes, France
Zarski, D., Nynca, J., Le Cam, A., Klopp, C., Montfort, J., Fontaine, P., Ciereszko, A., Bobe, J.